Find Anesthetic Tetracaine HCl, CAS 136-47-0, 136-47-0 In Stock on Industry Directory, Reliable Manufacturer/Supplier/Factory from China.

Inquiry Basket (0)
Home > Products > Spinal Surgery System > Anesthetic Tetracaine HCl CAS 136-47-0

Anesthetic Tetracaine HCl CAS 136-47-0

Anesthetic Tetracaine HCl CAS 136-47-0

    Payment Type: L/C,T/T,D/P,Paypal,Money Gram,Western Union
    Terms of Trade: FOB,CFR,CIF,EXW,FCA,CPT,CIP
    Min. Order: 10 Gram
    Delivery Time: 7 Days
    Packaging: As Buyer's Request
    Productivity: 100Ton
    Brand: Tianfu
    Transportation: Ocean,Land,Air,DHL,TNT
    Place of Origin: China
    Supply Ability: 50Ton
    Certificate: ISO
    Port: Shanghai port,Qingdao port

Basic Info

Model No.: TF-2106

Product Description

product name: tetracaine hcl

synonyms:tetracaine hydrochloride ,2-dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; amethocaine hydrochloride

cas : 136-47-0

molecular formula: c15h25cln2o2
molecular weight: 300.82
einecs: 205-248-5
appearance: fine white crystalline and odorless powder
melting point: 145~150 degree
assay: 99%
grade: pharmaceutical grade
usage: local anesthetic; mainly used in mucosa anesthetic. the function is stronger than procaine .



product description:

1. tetracaine hcl is synthesized from 4-butylaminobenzoic acid. the ethyl ester is formed through an acid-catalyzed esterification reaction. base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.


2. tetracaine is the t in tac, a mixture of 5 to 12 per cent tetracaine, 5? (per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) adrenaline, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.


3. it is on the world health organization's list of essential medicines, a list of the most important medication needed in a basic health system.a systematic review and meta-analysis of randomised controlled trials investigated tetracaine for use in emergency departments, especially for iv cannulation in children, in view of its analgesic and cost-saving properties - however it did not find a statistically significant improvement in first attempt cannulations.






specifications:



items

quality standards

results

description

white or almost white crystalline powder

white crystalline powder

solubility

matching with the working standard

complies


identification

a.by ir, to match with working standard

complies

b: to 10ml of solution s add 1ml of ammonium thiocyanate solution r.a white,crystalline precipitate is formed which,after recrystallisation from water r and drying at 80ºc for 2h,melts at about 131ºc


complies

c. to about 5mg add 0.5ml of fuming nitric acid r .evaporate to dryness on a water-bath,allow to cool and dissolve the residue in 5ml of acetone r.add 1ml of 0.1m alcoholic potassium hydroxide.a violet colour develops

complies


d. solution s gives reaction of chlorides.

complies

ph

4.5~6.5

5.78

residual solvents

conform to standard

complies

claruty

solution should be clear

complies

related substances

conform to standard

complies

heavy metals

≤10ppm

<10ppm

loss on drying

≤1.0%

0.87%

resiue on ignition

≤0.1%

0.05%

melting range

148ºc

147.5ºc~150.8ºc

assay(*)

99%~101.0%

100.40%

conclusion

the sample complies with specification of ep8



applications:

1.tetracaine (inn, also known as amethocaine; trade name pontocaine. ametop and dicaine) is a potent local anesthetic of the ester group. it is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.


2.in biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. tetracaine is an allosteric blocker of channel function. at low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

201505051132217343

Henan Tianfu Chemical Co.,Ltd

 In 2011 we entered the fine chemical market of Noble Metal Catalyst ,Organic Phosphine Ligands and OLED intermediates.With the joint efforts of our senior experts and professional technicians, Tianfu has developed more than 500 compounds, which are widely used in the fields of production and life science. The objective of the company is to put quality first and put our customer`s needs first – the satisfaction of our customers is the company`s ultimate goal. Improving product quality and service level is our responsibility, and creating more value for our customer`s is our purpose. We are constantly striving to make Henan Tianfu a leading chemical supplier, and hope to create a better future with you. Our company engages in Pesticide intermediate medical intermediate, development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won [High-tech Enterprise" by provincial government in 2013.

Company Info

  • Company Name: Henan Tianfu Chemical Co.,Ltd
  • Representative: Anson Zhang
  • Product/Service: UV-Curing Materials , Photoinitiators , Electronic chemicals , Ionic Liquids , Pharmaceutical Intermediates , Battery Electrolyte
  • Capital (Million US $): 1000000RMB
  • Year Established: 2009
  • Total Annual Sales Volume (Million US $): US$5 Million - US$10 Million
  • Export Percentage: 71% - 80%
  • Total Annual Purchase Volume (Million US $): US$5 Million - US$10 Million
  • No. of Production Lines: 3
  • No. of R&D Staff: 21 -30 People
  • No. of QC Staff: 5 -10 People
  • OEM Services Provided: yes
  • Factory Size (Sq.meters): 3,000-5,000 square meters
  • Factory Location: Kexuedadao No.168,high and new tech development zone,Zhengzhou city, China
  • Contact Person: Mr. Anson
  • Tel: 86-371-55170693
Email to this supplier
  • *Subject:
  • To:

  • *Messages:
    Your message must be between 20-8000 characters